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I hope that things are going well for you in London!  Over the years I've spent a lot of time in Manchester and in parts of Scotland but only visited London briefly.

Tschuss!
Hunter

(Sorry in advance to any Mancunian Amaz0ns members).

Manchester!? 😮  Poor you! 😀

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Look, stop bashing London. It's great. It's got rides, the statue of Liberty, and the Taj Mahal… waitaminute.

That was MONUMENTVILLE!

(ahem)

Welcome to the UK Rachel. I'm sure I'll see you soon should this 'meet up' we have planned for some time in the next month or two take place. ^___^

I agree – stop bashing London.  It can boast Ken Livingston, the Congestion Charge, the Milennium Dome.  Wait a minute, that was LONDON!

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Thanks for the complement, Fett – I hope I'll read a few more in future if I behave myself! ;D

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Oh dude, for cying out loud it was just a joke.  Fett is always like that, don't take everything so seriously.  Of course if you've got autism well then not much you can do about that, but anyway it's just a joke and the article is fine.

The_Collector:
Mine was just a joke as well – its why I ued the grinning emoticon after joking with Fett about the comic randomness of what he said. I was just concerned that people may have thought I was being arrogant by sticking my nose in and coming the "expert" without it being wanted.  I certainly wasn't reacting badly to Fett's tongue-in-cheek humour – I was playing along with it.

The Muffin Man -I don't watch the Simpsons – Homer drives me up the wall, so I didn't know the quote, but I guessed that Fett was joking about being confused by my rambling and rather incoheren tattempts at clarifying one or two slight misunderstandings people on the board were having with the science involved. 

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My cat's breath smells like cat food.

Er, 'scuse me Mr Fett, have the high winds we've had in the UK done something to you!? ;D
I haven't got a clue what you're on about, sorry! :-[ ???
I hope you good folks here don't think I was being presumptuous or arrogant in what I wrote – I just thought I might be able to offer an jargon-free synopsis of the paper's abstract, which is the summary of the rest of the paper for those scientists who don't have time to read the whole thing but who want to know the essential theory behind the research and conclusions the paper draws.
<<Quietly leaves via back door, embarrassed.>>

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Sorry Lingster – got to disagree – I'd say I'm 98% sure it's the same (very attractive) lady. 8)

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Might I, as a Biologist, step in here?
Myostatin is a regulatory protein manufactured by the body to limit muscle growth; in other words, it stops it from growing in an uncontrolled, runaway fashion.  I actually did my 3rd-year Undergraduate resarch project on another, related signalling protein in the same (TGF-Beta) family as myostatin.  This team has, apparently found that an injected form of the cell-surface receptor for another developmental (growth) protein called activin "mops-up" the myostatin molecule, which blocks or reduces the strength of the signal it imparts, which is "stop growing muscle".  In normal circumstances, myostatin and other signalling proteins that increase muscle growth will work in harmony to provide the right amount of muscle tissue; however in genetic diseases and conditions where muscle growth is impeded by other means, lifting the myostatin restriction on muscle growth would help bring the muscularity up o normal levels.

We must, however, be careful about removing restrictions on muscle growth in healthy individuals for aesthetic or commercial reasons.  A similar regulatory mechanism which controls the rate of normal cell division, when disrupted by mutation, can often lead to fatal cancers, as cells in a particular body tissue keep multiplying indefinitely.  I doubt this would be the case here, but removing one part of a complex signalling network could have unforeseen effects that may be dangerous.  I've only as yet read the abstract to this paper, but I think there's a LONG way to go (if it ever happens) before myostatin pathway inhibition could become a commercially-available treatment for those wanting to increase muscularity.

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What is it about Canada?  They must have more beautiful FBBs per head of population than anywhere else.  This lady is yet another example to those more mature ladies that hard work will lead to people underestimating your age genuinely, and not just out of diplomacy.

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She has changed a lot between old and new careers.  I think (no, I know) that, having come across this lady for the first time here, I prefer her as she was in her FBB days.  Whoever said about her smile was right – that smile is almost as melting as my favourite Amazon Princess's 😮 (and from me, that's high praise indeed).  It occurs to me that some ladies look best in the more relaxed style of bodybuilding, and, although she's still beautiful, I think Ms Hoshor may well be one of those.
On a side issue, one of the photos showed Denise (and the photographer) on what was clearly a double-track railway line (sorry, railroad).  I'm a railway enthusiast as well as an FBB lover (my first and greatest passion is motorsport, however, but that's a whole other story), and I can confirm that trespassing on the railways in Britain is a very serious offence.  Right from the early days, railways in rural areas had to be fenced-off to stop livestock from being hit by trains (hence why British locos never had cowcatchers like US locos have), and, given that most of our trains are shorter, lighter and quite a bit quicker than in the US (most UK freight does around 50-60 mph, and, other than on single-track branch lines, passenger trains hit anything between 70 and 125 mph, the consequences of trespassing are very serious.
I therefore found the aforementioned photo somewhat alarming – are any US Amaz0ns members also knowledgeable about US railroad practice and whether doing this sort of thing is taken very seriously over there?

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I'm not wild about the drawn-on Vulcan eyebrows she's got going on, but she hits one of the best most-muscular poses ever.

Agreed – she seems in some of her photos to be going for a slightly surreal image – some of her facial expressions remind me bizarrely of Salvador Dali (similar eyebrows) 😮  She has got one heck of a body, though. 😉

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